Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d5a5ae085853db5173d99daca7b6669 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2123-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0448 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
filingDate |
1997-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2001-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a1dab1ad114d5c30d36b7c18a120fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_503f12c2195998992207bf7d354b6432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01f4a45de34251827624003f24db1de3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26cbc1c532d77018077aab876b6843b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20e17cafba496b54f6686ca298b21330 |
publicationDate |
2001-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6180083-B1 |
titleOfInvention |
Tropane derivatives useable in particular for in vivo detection of dopamine transporters |
abstract |
The present invention relates to tropane derivatives having particular use for the in vivo detection of dopamine transporters. n These derivatives meet the formula n in which R 1 is I or Sn (R 3 )3, R 2 is for example the methyl group, and X and Y are various substituents. n The derivatives with X═CH 3 and Y═H show strong specificity for the dopamine transporter compared with the serotonin transporter (74% inhibition when the transporter is previously saturated with GBR 12909). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2013084244-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005013500-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9028802-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009055922-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8986653-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9757483-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009297446-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8574545-B2 |
priorityDate |
1996-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |