http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6174713-B1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4432a43459a5de46f4a04b577898fd0
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01002
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
filingDate 1997-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2001-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5edb52b358fea7e72759a36d14b12ea2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f737add581c12e426184a7f3b37c449a
publicationDate 2001-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6174713-B1
titleOfInvention Candida cytoplasmic tryptophanyl-tRNA synthetase proteins, nucleic acids and strains comprising same
abstract The present invention relates to isolated and/or recombinant nucleic acids which encode Candida cytoplasmic tryptophanyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida cytoplasmic tryptophanyl-tRNA synthetase or portion thereof. Also disclosed are constructs comprising the nucleic acids of the present invention, host cells comprising a recombinant nucleic acid or construct, and methods of producing a Candida cytoplasmic tryptophanyl-tRNA synthetase, portion thereof, or fusion protein comprising the same. Also described are tester strains, which are cells engineered to rely on the function of a Candida cytoplasmic tryptophanyl-tRNA synthetase or functional fragment thereof encoded by an introduced cloned gene, and which can be used in a method of detecting an inhibitor of Candida cytoplasmic tryptophanyl-tRNA synthetase function. The invention further relates to isolated and/or recombinant Candida cytoplasmic tryptophanyl-tRNA synthetases, portions thereof, or fusion proteins comprising a Candida cytoplasmic tryptophanyl-tRNA synthetase or portion thereof, methods of use of these polypeptides in an assay to identify inhibitors of Candida cytoplasmic tryptophanyl-tRNA synthetase function, and antibodies reactive with Candida cytoplasmic tryptophanyl-tRNA synthetases.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021010799-A1
priorityDate 1997-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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