| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4712 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 |
| filingDate |
1999-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6096d6768df675a3c612d71f2aff163d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4085fa22d22c09c849ff4041597b3dbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08cab5bd6fe88ac6c08145d2f44cceca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19e2709d622482cb7e458a4a7dcefbdc |
| publicationDate |
2000-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6165781-A |
| titleOfInvention |
Modified adeno-associated virus vector capable of expression from a novel promoter |
| abstract |
Described herein are constructions of recombinant DNA comprising modified adeno-associated virus (AAV) DNA sequences capable of functioning as a eukaryotic expression vector for expressing foreign DNA sequences using a novel transcription promoter comprising the termini of AAV DNA. It is shown that expression of a test reporter gene can be obtained from this vector in mammalian cells. It is further shown that this combination of vector and promoter can be used to introduce and express a human gene and correct a genetic defect in human cells resulting from malfunction of the mutant endogenous gene. Further, the vector can be used to correct the genetic defect by expressing a modified version of the human gene consisting of a fusion of part of the said gene and a synthetic sequence contained in the vector. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846729-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6893865-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003175974-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6821511-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8093054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002012997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008076730-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206197-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007087433-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6936466-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005148076-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8221738-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011104117-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6596535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2181704-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6924128-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7785888-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006019382-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7125717-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9415119-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8636998-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10369193-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003219735-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9375491-B2 |
| priorityDate |
1992-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |