abstract |
PCT No. PCT/SE96/00372 Sec. 371 Date Sep. 23, 1997 Sec. 102(e) Date Sep. 23, 1997 PCT Filed Mar. 25, 1996 PCT Pub. No. WO96/29083 PCT Pub. Date Sep. 26, 1996The invention refers to the use of Lactobacillus plantarum 299v having a mannose-specific adhesin for the preparation of a pharmaceutical composition inhibiting the binding of pathogenic bacteria expressing mannose-specific adhesins to the epithelial cell surface. The strain of Lactobacillus plantiarum which can be used in the invention adheres to D-mannose-coated agarose beads. The invention also refers to the use of said strain for the preparation of a pharmaceutical composition to be used in prophylatic and/or curative treatment of bacterial translocation, gastroenteritis and other diseases caused by pathogenic bacteria expressing mannose-specific adhesins. |