| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a448c358dabbe3fba9b93a9309b7992
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d4c0ee8a85a8161fe70c3bfefe01a53 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-09 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-887 |
| filingDate |
1998-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f8a115b4648f2a220acf59992712046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90f246916e12efda531568698a4dc200 |
| publicationDate |
2000-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6153747-A |
| titleOfInvention |
Process for the preparation of 2-halomethyl-penems and their use for the preparation of antibacterial penems |
| abstract |
Process for the preparation of 2-halomethyl-penems (I) comprising (a) reacting an acetoxy-(protected hydroxyethyl)-2-azetidinone (III) with a 2-halothioacetic acid to form a 3-haloacetylthioazetidinone (V), (b) reacting (V) with oxalyl chloride to give an intermediate (VII), acylated on the beta-lactamic nitrogen, and (c) cyclizing (VII) in the presence of an organic phosphate or phosphonite to produce the corresponding 2-halomethyl-penem (I). |
| priorityDate |
1996-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |