abstract |
PCT No. PCT/GB96/02333 Sec. 371 Date Jul. 6, 1998 Sec. 102(e) Date Jul. 6, 1998 PCT Filed Sep. 19, 1996 PCT Pub. No. WO97/11083 PCT Pub. Date Mar. 27, 1997The invention concerns novel compounds having defined structural formulae and methods of mutating a nucleic acid sequence, the method comprising replicating a template sequence in the presence of a nucleoside triphosphate analogue in accordance with the invention, so as to form non-identical copies of the template sequence comprising one or more nucleoside triphosphate analogue residues, and a kit for use in performing the method of the invention. |