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filingDate 1998-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fc5904eb55385e77ae73f38a38dcd60
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publicationDate 2000-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6140066-A
titleOfInvention Methods of cancer diagnosis using a chimeric toxin
abstract The present invention relates to methods for cancer diagnosis using a chimeric toxin. In particular, the invention relates to the use of a chimeric toxin composed of gonadotropin releasing hormone (GnRH) and Pseudomonas exotoxin A (PE) to detect a tumor-associated epitope expressed by human adenocarcinomas. Mutated GnRH-PE molecules that bind but do not kill tumor cells are exemplified.
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