http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6137009-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_932fd4ede9ad1ea96beef781d3583626 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-08 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-29 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-08 |
| filingDate | 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d4afc4444ffa61481905173480676b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbf87e77c718c0cfeca0aa3b34efee5a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5d53ad4fce788bdb1795ec6d275170e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b19dece3ad9d69daec1b6a313a01e2a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7817a73b573c04c7de6d48da4ddab383 |
| publicationDate | 2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6137009-A |
| titleOfInvention | Method of manufacturing flumetralin |
| abstract | The invention is a process to manufacture the intermediate secondary amine N-ethyl-2-chloro-6-fluoro-benzylamine, and then the process of reacting this intermediate to manufacture the herbicide flumetralin. Equimolar quantities of monoethylamine, sodium hydroxide, and 2-chloro-6-fluorobenzyl chloride are reacted at a temperature between about 70 DEG C. and about 100 DEG C. in a composition containing at least 2.5 times the required quantity of monoethylamine. The reagent monoethylamine functions as solvent and heat sink for the reaction, and also minimizes the formation of undesired byproducts. The excess monoethylamine is removed after formation of the intermediate. Then, equimolar quantities of sodium hydroxide in water and molten 4-chloro-3-5-dinitrobenzotrifluoride are added to the intermediate, and the temperature is controlled between about 90 DEG C. and about 115 DEG C. The product of this reaction is relatively pure, i.e., 98 percent by weight, molten flumetralin. It is advantageous to wash the product with boiling water to facilitate removal of salt and excess sodium hydroxide. |
| priorityDate | 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 125.