abstract |
PCT No. PCT/US97/06726 Sec. 371 Date Feb. 22, 1999 Sec. 102(e) Date Feb. 22, 1999 PCT Filed Apr. 21, 1997 PCT Pub. No. WO97/43307 PCT Pub. Date Nov. 20, 1997The present invention provides compounds that inhibit the association of platelet-derived growth factor and phosphatidylinositol 3-kinase. The present invention also provides pharmaceutical compositions that contain a compound that inhibits the association of platelet-derived growth factor and phosphatidylinosital 3-kinase, and methods of treating cancer, restenosis, arthritis, dermatitis, atherosclerosis, vein graft intimal hyperplasia, neointimal hyperplasia of vascular smooth muscle and psoriasis using compounds that inhibit the association of platelet-derived growth factor and phosphatidylinositol 3-kinase. |