| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3c9fc3cb0028234aedb8df651f9d2e4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1858 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 |
| filingDate |
1999-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b911ecf2ed34d7267e6b3db00631d347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cccccf547f6c52b1d0170fb9591a09ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73e00a8e3586d75bba412e2010b329a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a402388594b79b7ce2393f091eaa078d |
| publicationDate |
2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6136785-A |
| titleOfInvention |
Protection from loss of sensory hair cells in the inner ear by administration of insulin-like growth factor and platelet derived growth factor |
| abstract |
The invention relates to a method for protecting sensory hair cells of the inner ear from damage caused by ototoxic drugs, in particular, aminoglycoside antibiotics, by administering to a vertebrate a growth factor, or mixture thereof. Additionally, the method protects against loss of sensory hair cells as a result of aging. In particular, the growth factor is an insulin-like growth factor or platelet-derived growth factor. The invention also relates to a method for detecting protection against an ototoxic drug on sensory hair cells of an inner ear of a vertebrate by a growth factor or biologically active fragment. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6927204-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7390482-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6593290-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006233755-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6653279-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6268351-B1 |
| priorityDate |
1995-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |