| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e759962aa10be581ae05600019cfadcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
1997-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d207b09c3475455770c1fed3ae19eeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cdc1638031a17f18e36c327b5505fb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51a67f68217b9b65eafa6630b1d1b7f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aefb817c83a130ec07760a0eb388e6a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4188305f35568587e8b53ee65605d406
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef396561bc25dae81752cb176ed23f67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ef239cae8b481b81df2ad7505ffbc11 |
| publicationDate |
2000-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6136532-A |
| titleOfInvention |
Methods for treating bipolar mood disorder associated with markers on chromosome 18q |
| abstract |
The present invention is directed to methods of detecting the presence of a bipolar mood disorder susceptibility locus in an individual, comprising analyzing a sample of DNA for the presence of a DNA polymorphism on the long arm of chromosome 18 between markers D18S469 and D18S554, wherein the DNA polymorphism is associated with a form of bipolar mood disorder. The invention for the first time provides strong evidence of a susceptibility gene for bipolar mood disorder that is located in the 18q22-q23 region of the long arm of chromosome 18. The disclosure describes the use of linkage analysis and genetic markers in this 18q22-q23 region to fine map the region and the use of genetic markers to genetically diagnose (genotype) bipolar mood disorder in individuals, to confirm phenotypic diagnoses of bipolar mood disorder, to determine appropriate treatments for patients with particular genotypic subtypes. Isolated polynucleotides useful for genetic linkage analysis of BP-I and methods for obtaining such isolated polynucleotides are also described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003064401-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2357478-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7101666-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6570567-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006134625-A1 |
| priorityDate |
1996-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |