| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5db6243e0edb49c2d3e7af3f5580b7fd |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-10 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-35 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
1999-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_845f4426dcc727768e9e8511c4640d7f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13dbed2ce33d68bc591616b60495f31c |
| publicationDate |
2000-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6132713-A |
| titleOfInvention |
Arginine deiminase derived from mycoplasma arthritidis and polymer conjugates containing the same |
| abstract |
A purified arginine deiminase (ADI) obtained from Mycoplasma arthritidis having the amino acid sequence of SEQ ID NO:2 as well as an isolated nucleic acid molecule containing a nucleotide sequence encoding the amino acid sequence set forth in SEQ ID NO:1 are disclosed. Other aspects of the invention include an expression vector, a cloned gene for expressing the Mycoplasma arthritidis derived ADI, (recombinant) host cells useful in expressing the ADI of the present invention and substantially non-antigenic polymer conjugates containing the ADI of the present invention as well as methods of treating arginine deiminase susceptible conditions in mammals. The arginine deiminase-polymer conjugates have high levels of retained enzyme activity and relatively long circulating lives. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10407482-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8568706-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9789170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0244360-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6737259-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0244360-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005129706-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106794229-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7323167-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106794229-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6635462-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010254943-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004258675-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008200641-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2444499-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11235037-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015143006-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2395099-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3954393-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2581450-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004062748-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7829659-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10463721-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7632492-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3888691-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2535347-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8129330-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008125347-A1 |
| priorityDate |
1997-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |