| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-2408 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 |
| filingDate |
1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99ab98721ce276860d60a456c247cf50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_402ab2b3a232e3780a0074cf4f562bdf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46052b8a03f6567e74a0e60281e69027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5238913e91a197797a76b8cd0a66be09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98adfa256d9da4ef7149f3004c0f23d1 |
| publicationDate |
2000-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6127566-A |
| titleOfInvention |
Process for the synthesis of O,O-dimethyl phosphoroamidothioate |
| abstract |
The present invention provides a continuous process for making O,O-dimethyl phosphoroamidothioate. In accordance with this process, O,O-dimethyl phosphorochloridothioate is reacted with ammonia and sodium hydroxide; addition of the sodium hydroxide controls the pH of the reaction mixture. The formed reaction mixture contains an aqueous phase and an organic phase. The organic phase of the reaction mixture is separated from the aqueous phase; a second organic phase is solvent extracted from the aqueous phase; and the resultant O,O-dimethyl phosphoroamidothioate is isolated from the combined organic phases via vacuum solvent stripping. In an embodiment of the present invention, the reaction of O,O-dimethyl phosphorochloridothioate with ammonia and sodium hydroxide is carried out in the presence of a solvent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11198700-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2019306638-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2021533184-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020018914-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116332989-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114213456-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101486731-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I764016-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10669295-B2 |
| priorityDate |
1998-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |