| abstract |
PCT No. PCT/RU95/00285 Sec. 371 Date Aug. 18, 1998 Sec. 102(e) Date Aug. 18, 1998 PCT Filed Dec. 28, 1995 PCT Pub. No. WO97/24354 PCT Pub. Date Jul. 10, 1997Substituted 6-R-1,3,4-thiadiazin-2-amines of the following general formula: wherein Ar is phenyl or phenyl optionally substituted with one or more chloro, bromo atoms, C1-C4 alkoxy or C1-C4 alkyl groups; R1 and R2 are each independently hydrogen atom or C1-C4 alkyl moiety; and R3 and R4 are independently selected from C1-C4 alkyl groups and pharmaceutically acceptable salts thereof, the use of them as anaesthetics, cardiovascular and hypometabolic agents and pharmaceutical compositions containing them. |