| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-832
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-285
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-56911 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-285 |
| filingDate |
1994-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8d119a006d1491e6bc6d6bf8ab6d0f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f60cefde5fc0fc4dbc8a9db2505b1442 |
| publicationDate |
2000-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6110470-A |
| titleOfInvention |
Pasteurella multocida toxin derivatives |
| abstract |
A vaccine for immunizing animals against diseases caused by microorganisms producing an osteolytic toxin comprising an immunologically effective amount of a recombinant, immunogenic, detoxified Pasteurella multocida toxin or toxin analog, the vaccine being encoded by a nucleotide sequence coding for a Pasteurella multocida toxin or toxin analog which is inserted in an expression vector capable of replicating in a suitable host microorganism in which the said sequence may be expressed. Optionally, the produced toxin or toxin analog is subjected to posttranscriptional modifications to provide the detoxified toxin or toxin analog. Alternatively, the nucleotide sequence may be modified prior to insertion into the expression vector so as to provide the toxin or toxin analog in a detoxified form. Furthermore, the use of a monoclonal antibody against Pasteurella multocida toxin or toxin analog, a labelled DNA sequence homologous to a DNA sequence coding for a toxin or toxin analog, and the toxin or toxin analog per se as diagnostic agents are described. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009238842-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101496899-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006039923-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005220812-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1657248-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1657248-A3 |
| priorityDate |
1988-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |