| abstract |
For the treatment of cancer, inflammation, and other conditions associated with matrix metalloproteinases or that are mediated by TNFα or enzymes involved in the shedding of L-selectin, CD23, the TNF receptors, IL-1 receptors, or IL-6 receptors, disclosed are compounds of the general formula n n B--X--(CH.sub.2).sub.m --(CR.sup.1 R.sup.2).sub.n --W--COY. |