| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7859f31a2d2be77be5e120bd1a93608b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2121-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0636
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0011 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate |
1997-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5649af321559bf24acb60e39edb3563a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5659ec129841647db2ce4dee6afd6ae |
| publicationDate |
2000-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6093381-A |
| titleOfInvention |
Modulation of the sensitivity of tumor cells to chemotherapeutics |
| abstract |
Disclosed is a method for improving the treatment of a cancer patient which is undergoing (adjuvant) chemotherapy. Prior to or concomitant with the patient receiving adjuvant chemotherapy, the patient is administered mitogenically stimulated lymph node lymphocytes or the supernatant therefrom. The lymph node lymphocytes are patient excised lymph node lymphocytes enriched in tumor reactive cells, such as CD4+ tumor reactive cells. Radiolabeled locators (e.g., antibodies) can be used along with a portable radiation detector to intraoperatively determine which lymph nodes bear lymph node lymphocytes enriched in tumor reactive cells. The patient excised lymph node lymphocytes enriched in tumor reactive cells then are subjected to mitogenic stimulation for their expansion and administration to the patient. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197267-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005287065-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8148696-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0245201-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923694-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9494696-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11426462-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0245201-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008228049-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7966054-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8344331-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003012731-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002102212-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8653469-B1 |
| priorityDate |
1994-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |