| abstract |
A class of substituted oxazolyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II wherein R is selected from halo, mercapto, hydroxyl, lower carboxyalkylthio, lower haloalkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, lower alkoxy, aryloxy, lower alkylamino, aminocarbonyl, lower alkoxyalkyl, and lower carboxy(haloalkyl); wherein R2 is selected from lower alkyl and amino; and wherein R4 is selected from hydrido, lower alkyl, lower alkylamino, lower alkoxy and halo; or a pharmaceutically-acceptable salt thereof. |