| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b37014766a57d712bba498b84d48e0ef |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8209
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8242
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8282
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8274
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-415 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-65 |
| filingDate |
1997-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7b3e01befc7761221be5800a9b472cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d7afe6f69f77ea0b28bee82848a3f01 |
| publicationDate |
2000-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6060646-A |
| titleOfInvention |
Tolerance of trichothecene mycotoxins in plants and animals through the modification of the peptidyl transferase gene |
| abstract |
Fusarium graminearum is a plant pathogen, attacking a wide range of plant species including corn (ear and stalk rot), barley, and wheat (head blight). Fusarium epidemics result in millions of dollars of loses in crop revenues. Fusarium graminearum infection in the cereals reduces both grain yield and quality. Mycotoxins are produced by many fungal Fusarium species and thus the grain becomes contaminated with these mycotoxins, such as the trichothecenes. The major trichothecene produced by F. graminearum is deoxynivalenol (abbreviated as DON, also known as vomitoxin). Trichothecenes are potent protein synthesis inhibitors and are quite toxic to humans and livestock. A yeast gene has been identified which is resistant to the trichothecene, trichodermin. A corresponding plant gene has been prepared, which has been used to transform plants and would be suitable to transform animals. These transformed plants have an increased resistance to Fusarium infestation. Potentially, transformed animals could have an increased tolerance to the trichothecene mycotoxins. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7235715-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6855872-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6646184-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006005271-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6346655-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010146667-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005114927-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8026410-B2 |
| priorityDate |
1997-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |