http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6060599-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0f4f8190960626ec922a1f03bcd4aba |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate | 1998-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82cffe73fc337d82e5f492213e0bacdb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_faa9a5ea071c3b0e6701959d2572fc76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1f196ffb8d41fc6949d0d2e087d5f7f |
| publicationDate | 2000-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6060599-A |
| titleOfInvention | Process for the preparation of cefuroxime axetil in an amorphous form |
| abstract | A process for preparing cefuroxime axetil in substantially amorphous form comprises forming a mixture of crystalline cefuroxime axetil and at least one pharmaceutically acceptable excipient, and subjecting the mixture to milling for a period of time sufficient to convert the crystalline cefuroxime axetil to substantially amorphous form, i.e., the crystallinity is less than 5%. The amorphous cefuroxime axetil has a chemical purity of at least 95%. Desirably, the particles of the milled material are reduced to a size of less than 2 mu m. The amorphous cefuroxime axetil prepared by this method may consist of R isomer, S isomer, or a racemic mixture of the R and S isomers. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7507813-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6346530-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006020130-A1 |
| priorityDate | 1997-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 53.