http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6054116-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef416fe4f66ebb1021cecfb0ba5ae45d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate | 1998-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5898a632ed2911d25645863cc19c304a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875873b66cf89055cb6c351054d148c8 |
| publicationDate | 2000-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6054116-A |
| titleOfInvention | Chimeric mouse for human and mouse immune systems |
| abstract | This invention is directed to a chimeric mouse capable of mounting murine cellular and humoral immune response, where the chimeric mouse is tolerant of human tissue implanted therein. The chimeric mouse of this invention is capable of developing murine T cells and producing murine IgG antibodies, which T cells and antibodies are tolerant of the human tissue implanted in the mouse. This allows for the challenge of the vaccinated mouse with human-specific pathogens and determining the capacity of the vaccine to protect the cells in the implanted tissue from infection. This invention is also directed to a method for the development of the chimeric mouse, as well as to the use of the chimeric mouse for the screening of vaccines for human-specific pathogens. |
| priorityDate | 1992-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.