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publicationDate 2000-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6048701-A
titleOfInvention Antibody detection of mismatch repair proteins
abstract Antibodies directed to human protein mismatch repair proteins can be used diagnostically to discriminate between proliferating and non-proliferating cells. In addition, they can be used to determine whether cells have a mismatch repair defect caused by a mutation in e.g., hMSH2, hMLH1, or hPMS2. They can also be used to monitor the efficacy of anti-neoplastic therapies.
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