| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-20 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-087
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01V3-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ea2fadc64b4a9227753347a68c5798a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13860e061f997b0ee474cf85ed94d43e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_568e828753ce63deb38775cc95c13e91 |
| publicationDate |
2000-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6043024-A |
| titleOfInvention |
Use of one-dimensional nuclear magnetic resonance to identify ligands to target biomolecules |
| abstract |
The present invention provides a process for identifying compounds which bind to a specific target molecule. The process comprises the steps of: a) generating a first T2- or diffusion-filtered proton spectrum of one or a mixture of chemical compounds; b) exposing one or a mixture of chemical compounds to the target molecule; c) generating a second T2- or diffusion-filtered proton spectrum of one or a mixture of chemical compounds that has been exposed the target molecule in step (b); and d) comparing said first and second T2- or diffusion-filtered proton spectra to determine differences between said first and said second spectra, the differences identifying the presence of one or more compounds that are ligands which have bound to the target molecule. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004259092-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003077224-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2001051333-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006166279-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007127830-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7377894-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003148343-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010041021-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10416256-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7061237-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009311670-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6818202-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005030026-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7385395-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003092027-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7146277-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007256148-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002042150-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008090270-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7595170-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8933209-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2586787-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006030031-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009136970-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004086948-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6683455-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9678185-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007184455-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008118951-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6677160-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002182650-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6764858-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003143757-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7037660-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03040400-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003165431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03040400-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002127731-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6979531-B2 |
| priorityDate |
1997-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |