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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06
filingDate 1992-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2000-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8508c9e902fd383083bffe11c66c6cfa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_813faa4e8fa34b12e9f9f2a5e6028f1e
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publicationDate 2000-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6040298-A
titleOfInvention Methods for treatment with compositions effective against acyclovir-resistant strains of herpes viruses
abstract The present invention relates to pharmaceutical compositions useful for the treatment of subjects suffering from an infection or disease caused by herpes virus strains that are resistant to treatment with acyclovir. In particular, it has been discovered that the low dosage amounts of 1-(2'-deoxy-2'-fluoro- beta -D-arabinofuranosyl)-5-iodouracil (FIAU) are effective in inhibiting replication of acyclovir-resistant HSV strains. The present invention is also directed to methods of the preparation of pharmaceutical antiviral compositions and to the methods of their use in the treatment of infection or disease.
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priorityDate 1992-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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