| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
1998-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79b5da156a762fe59257252919a036b6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db268020fe9a1b8f27916fe5303bc3b5 |
| publicationDate |
2000-02-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6030783-A |
| titleOfInvention |
Photo-potentiation of cisplatin chemotherapy |
| abstract |
Methods disclosed herein capitalize on the discovery that DNA Structure Specific Recognition Proteins (SSRPs) can be induced to bind covalently to genomic lesions formed by chemotherapeutic agents, particularly cisplatin-type agents, by photo-irradiation with ultraviolet light. Methods and compositions based on this discovery are provided for sensitizing particular eukaryotic cells to killing by chemotherapeutic agents, particularly cisplatin-type drugs. Methods and compositions also are provided for potentiating cytotoxicity of a chemotherapeutic agent, particularly a cisplatin-type agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004258771-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103675072-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103675072-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010035853-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112916047-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110660120-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014113927-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9358291-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110660120-B |
| priorityDate |
1997-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |