| abstract |
Novel oxazolidinone derivatives of the formula I ##STR1## in which R 1 is a phenyl radical which is unsubstituted or is monosubstituted by CN, H 2 N--CH 2 --, A 2 N--CH 2 --, H 2 N--C(═NH)--, H 2 N--C(═NH)--NH--, H 2 N--C(═NH)--NH--CH 2 --, HO--NH--C(═NH)-- or HO--NH--C(═NH)--NH--, n X is O, S, SO, SO 2 , --NH-- or --NA--, n B is ##STR2## A is alkyl having from 1 to 6 C atoms, R 2 is H, A, Li, Na, K, NH 4 or benzyl, n R 3 is H or (CH 2 ) n --COOR 2 , n E is, in each case independently of each other, CH or N, n Q is O, S or NH, n m is 1, 2 or 3, and n n is 0, 1, 2 or 3, n and physiologically compatible salts thereof are provided, which inhibit the binding of fibrinogen to the corresponding receptor and can be used for treating thrombosis, stroke, cardiac infarction, inflammations, arteriosclerosis, osteoporosis and also tumors. |