Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ee5285e8e8edccb061046ff20da7a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_386cb7617dc58288fcea755bb041387a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
1995-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2000-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fb61465f72bb18c3270e1774f064d8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_575b39e35db5ffb5e6cb83f809c78564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23f44905b15ef120ef9014a80bd35e9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e9d2efc916697b07bae73d08e48f4e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356891b366e8a2657958b3b7499d7cd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0cfbd9cba21f3b8eb4bd4cba04093c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a469c37748f62b30e11afe9411c1f71b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bf684a9cf9f3571cda45842f56f11f0 |
publicationDate |
2000-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6025142-A |
titleOfInvention |
Hydrophobic u-PAR binding site |
abstract |
The invention relates to an antibody which inhibits the binding between u-PA and u-PAR to an extent of at least 90% in an assay as defined in the specification, or an active fragment or immunological equivalent of said antibody. Examples of such antibodies are deposited Jul. 7, 1994 at Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSM) with accession numbers DSM ACC2178 and DSM ACC2179 under the terms and conditions of the Budapest Treaty. The invention furthermore relates to a method for detecting or quantifying u-PAR or a glycosylation variant of u-PAR in a sample by use of an antibody according to the invention. Furthermore, the invention relates to a method for the manufacture of a therapeutic agent for preventing or counteracting localized proteolytic activity using of an antibody of the invention as well as to use of an antibody according to the invention for the preparation of a diagnostic agent which is capable of targeting a diagnostic to a cell that contains a u-PAR on the surface. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008199476-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004265229-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004063605-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8105602-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011123029-A1 |
priorityDate |
1994-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |