| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_82980f9308582ae872148dad95e35c44 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-685
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1272 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate |
1998-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2532223d03bbde75cbe07d20e9b811e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f82e0179c6b50ffe0c2709b8c4184f0 |
| publicationDate |
2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6022560-A |
| titleOfInvention |
Pharmaceutical compositions, novel uses, and novel form of α-tocopherylphosphocholine |
| abstract |
alpha -Tocopherylphosphocholine and salts thereof have been discovered to possess antiviral, anti-fungal, anti-inflammatory, PAF-antagonist, and ultra-violet radiation-blocking activities. The compound and salts have also been discovered to be capable of forming liposomes. The present invention thus provides methods of treating viral and fungal infections, inflammatory disorders and pathophysiological conditions due to PAF activity in a mammal by administering to the mammal alpha -tocopherylphosphocholine or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutical compositions comprising alpha -tocopherylphosphocholine or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier. Further, the invention provides liposomes which comprise alpha -tocopherylphosphocholine or a salt thereof as a structural component of the liposome bilayer. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004235938-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010303899-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003236301-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6417223-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8664264-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7300954-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004097431-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008161349-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7312232-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7608638-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7718814-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6770672-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008119514-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003208607-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8148424-B2 |
| priorityDate |
1996-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |