| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5d1de0cb099ee72980dadb3b90d66d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f92c32cd2a9e162c8934c42f7ba6c31c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-196 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-428
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-196
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-498
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate |
1997-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2000-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_362c6704d006da9b11d31683241b6da8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d28b1598fdaf1978b9ef4efefa22cb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e69539c9dc94e1f94e38652a9a3d18ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fddc78f58dfcdf05da58a518e88071f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fa1f6e24f5d6b786660aaf5f50682e4 |
| publicationDate |
2000-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6017940-A |
| titleOfInvention |
Compositions and methods for treating bone deficit conditions |
| abstract |
Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or "linker" defined as including a covalent bond per se so as to space the aromatic systems at a distance 1.5-15 Å, are effective in treating conditions associated with bone deficits. The compounds can be administered to vertebrate subjects alone or in combination with additional agents that promote bone growth or that inhibit bone resorption. They can be screened for activity prior to administration by assessing their ability to effect the transcription of a reporter gene coupled to a promoter associated with a bone morphogenetic protein and/or their ability to stimulate calvarial growth in model animal systems. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003147860-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9254301-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010136120-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8563040-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6372257-B1 |
| priorityDate |
1996-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |