| abstract |
The present invention provides novel methods of lowering serum cholesterol and inhibiting smoother muscle cell proliferation, particularly restenosis, in humans, and inhibiting uterine fibroid disease and endometriosis in women comprising administering to a human/woman in need of treatment an effective amount of a compound of formula I wherein R is C1-C6 alkyl, C1-C6 alkoxy, halo, or trifluoromethyl; R1 and R2 each are the same or different C1-C6 alkyl group; n is an integer from 2 to 6; and R3 and R4 each are independently C1-C4 alkyl, or combine to form a substituent selected from the group consisting of pyrrolidino, morpholino, piperidino, piperazino, 4-(C1-C6 alkyl)piperazino, and 4-phenyl-piperazino; or a pharmaceutically acceptable salt thereof. |