| abstract |
PCT No. PCT/GB95/01783 Sec. 371 Date Jan. 30, 1997 Sec. 102(e) Date Jan. 30, 1997 PCT Filed Jul. 27, 1995 PCT Pub. No. WO96/03151 PCT Pub. Date Feb. 8, 1996The invention provides a two component system for gene-directed enzyme prodrug therapy which comprises: (a) a vector which encodes a carboxypeptidase which is expressed within a cell; and (b) a prodrug which can be converted into an active drug by said carboxypeptidase, useful in the treatment of tumours. |