| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f8cfa5aee4410611b5c562275c9f8e3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 |
| filingDate |
1998-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_678b75c709fdfd5d13e7bb2fd2c18597
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4a3d36b911cc64a503760f3eeff9ce |
| publicationDate |
1999-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6001618-A |
| titleOfInvention |
Haloacetoacetate reductase, method for producing said enzyme, and method for producing alcohols using said enzyme |
| abstract |
A novel enzyme is provided. This enzyme is capable of reducing 4-haloacetoacetic acid esters to produce (S)-4-halo-3-hydroxybutyric acid esters with high optical purity. The enzyme was isolated from a microorganism belonging to the genus Kluyveromyces. Using the enzyme, (S)-4-halo-3-hydroxybutyric acid esters, which are useful as HMG-CoA reductase inhibitors, intermediates for synthesizing various medicines and agricultural chemicals, can be efficiently produced with high optical purity. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010209984-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006194297-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807423-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008280336-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004137585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7416865-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003134900-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7888083-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7132267-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008248539-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6855525-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7125693-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7157255-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6218157-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7879585-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8617864-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8273547-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7732171-B2 |
| priorityDate |
1997-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |