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publicationDate 1999-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5993801-A
titleOfInvention Gene therapy using stromal cells
abstract A method of causing production and secretion into the bloodstream of a human patient of a biologically active enzyme for which the human patient suffers a deficiency; the method involves introducing into the human patient donor bone marrow stromal cells which have been transfected with a gene encoding the enzyme, so that the introduced cells can adhere to a bone cavity surface of the patient and produce and secrete the active enzyme.
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