http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5990172-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eec77d02b62e7aac2aaed86de229dccc |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-28 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-78 |
filingDate | 1997-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2befc4da943ba10988b8a47af9c6d1d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cc116b83e1915c386943ccd19d190dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb0bb31641dfa28b5b5e38f2eb2aad7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2411654d899384a6e6d92eab267c9332 |
publicationDate | 1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5990172-A |
titleOfInvention | Peptidomimetics for the treatment of HIV infection |
abstract | This invention provides peptidomimetics which bind to T4 or CD4 cell receptors and are useful in inhibiting viral infectivity by viruses which bind to T4 cell receptors. More specifically, peptidomimetics of this invention can alleviate symptoms of AIDS by inhibiting binding of HIV, the virus associated with AIDS, to receptor sites in human cells susceptible to HIV infection. These peptidomimetics, in particular, inhibit binding of HIV to cells of brain membrane and the immune system. They also display substantially longer half-lives in vivo than peptide T. The compounds of this invention which bind to T4 or CD4 receptors and thereby inhibit binding of HIV, alone or in combination with one another, can be used to alleviate AIDS symptoms and ameliorate symptoms of HIV infection, especially neuronal dementias and Kaposi's sarcoma. The compounds of this invention, alone or in combination, can further be used to prevent development of AIDS in persons who might become exposed to HIV. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006068426-A1 |
priorityDate | 1996-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 452.