abstract |
Compounds of formula (I) in which R 1 and R 2 , which may be the same or different, is each selected from hydrogen, halogen or C.sub.(1-8) alkyl; R 3 is aryl or aryl C.sub.(1-4) alkyl which may be optionally substituted; X is a linker group; Y is an optionally substituted aryl group; and n is 0, 1 or 2; are inhibitors of the enzyme Lp-PLA 2 and thereof of use in treating atherosclerosis. |