| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-963
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-9027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-795 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
| filingDate |
1998-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fdd46991686ea2da54dd4a69e45c0718
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc3e4f600203b1da097869f309afcee1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a31ac1cf4e301c7228aff9a087fd3e44 |
| publicationDate |
1999-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5989844-A |
| titleOfInvention |
Method for evaluating drug metabolism and reagent compositions therefor |
| abstract |
This invention relates to a method for evaluating the susceptibility of pharmaceutical drugs to metabolism by a specific cytochrome P-450 isozyme, which comprises contacting the sample compound with a reagent composition prepared by adding the specific cytochrome P-450 isozyme to liver microsomes lacking said specific cytochrome P-450 isozyme in a carrier material. More particularly, this invention relates to a useful in vitro quantitative assay for drug metabolism by P-450 isozymes such as CYP2D6, CYP2C19, and CYP2A6. This invention also relates to a reagent composition which is useful for said in vitro assay. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2462933-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2468278-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005075794-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003211623-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8688416-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7983848-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011060532-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004096874-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011045481-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197813-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004199333-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011251834-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8084210-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6764855-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008312309-A1 |
| priorityDate |
1997-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |