http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5986095-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76195fd1cd08192222699d8e7a88c231 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C29-095 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-09 |
filingDate | 1992-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 1999-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe0c514156fcb645cd4a3c09168c6f82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a90a28c813b007ba3caffbe2d722b13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0279a08073f44cb844db9f61bc867d4 |
publicationDate | 1999-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-5986095-A |
titleOfInvention | Enantioselective preparation of halophenyl alcohols and acylates |
abstract | A process is described for preparing a compound of the formula or the S-enantiomer thereof, wherein: R is alkyl, aryl, cycloalkyl, aralkyl, or cycloalkylalkyl, R1 is halogen; R2 is halogen, alkyl, cycloalkyl, aryl or wherein the process comprises treating the associated racemic alcohol with an acylating agent (wherein L is a leaving group) and an enzyme or microorganism capable of enantioselective acylation. This process may also be used to isolate the unreacted R- or S-alcohol. The acylated product may be enantioselectively hydrolyzed with a lipase or lipase-supplying microorganism to the S- or R-alcohol. Compounds prepared by this invention are useful antipsychotic agents or useful intermediates therefor. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004037980-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004037980-A3 |
priorityDate | 1992-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 155.