| abstract |
PCT No. PCT/CA95/00290 Sec. 371 Date Mar. 20, 1997 Sec. 102(e) Date Mar. 20, 1997 PCT Filed May 4, 1995 PCT Pub. No. WO95/30900 PCT Pub. Date Nov. 16, 1995Compositions consisting of at least one TGFb receptor II homo 1b (TRH1b) subdomain or at least one TGFb receptor II homology 1 (TRH1) domain and a carrier, auxiliary or excipient. The TRH1b subdomain has a sequence with the following amino acid pattern: Cys-Xj-Lys/Arg-Xk-Ser/Thr-Xl-Cys-Xm-Asp-Xn-Asp/Glu, wherein Xj, Xk, Xl, Xm, Xn, represent any amino acid and j is 4 to 5, k is 2 to 6, 1 is 4 to 9, m is 0 to 2, and n is 5 to 6. The TRH1 domain has a sequence with the following amino acid pattern: Cys-Xh-Asn/Gln-Xi-Cys-Xi-Lys/Arg-Xk-Ser/Thr-Xl-Cys-Xm-Asp-Xn-Asp/Glu, wherein Xh, Xi, Xj, Xk, Xl, Xm, Xn, represent any amino acid and h is 8 to 14, i is 12 to 16, j is 4 to 5, k is 2 to 6, l is 4 to 9, m is 0 to 2, and n is 5 to 6. |