| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c7b34102e745f5a7ab0f6f6cb3aa91 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-775
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
1996-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22360db9900bf3b3c3d46da50bcbb875
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de95e81b6f4b76e5fa72ff6d867b2757
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3768d3ddea68a402e0283349a649dc91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dbfd18dc1d935b95487963fced4ee5b |
| publicationDate |
1999-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5976793-A |
| titleOfInvention |
Methods of transcriptionally modulating gene expression and of discovering chemicals capable as gene expression modulators |
| abstract |
The present invention provides a method of transcriptionally modulating the expression of a gene-of-interest. The method comprises contacting a cell which is capable of expressing the gene with an amount of a molecule effective to transcriptionally modulate expression of the gene and thereby affect the level of the protein encoded by the gene which is expressed by the cell. Molecules useful in the practice of the invention are characterized as follows (a) do not naturally occur in the cell, (b) bind to DNA or RNA or bind to a protein through a domain of such protein which is not a ligand binding domain of a receptor which naturally occurs in the cell. Additionally, this invention provides a method for determining whether a molecule known to be a modulator of protein biosynthesis is capable of transcriptionally modulating expression of a gene-of-interest. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006247192-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6596506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002168623-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004077080-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004115627-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0237077-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6479241-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7504230-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7189570-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7192771-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004161797-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7795509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003105045-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6911541-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004103454-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7645925-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0237077-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004031074-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003018997-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0060122-A1 |
| priorityDate |
1989-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |