| abstract |
Derivatives of camptothecin are disclosed and are represented by the general formula: wherein when R2 is H, R1 is a C2-C4 alkyl group, a C6-C15 alkl group, a C3-C8 cycloalkyl group, a C2-C15 alkenyl group or a C2-C15 epoxy group; and when R2 is a nitro group, R1 is a C1-C15 alkyl group, a C2-C15 alkenyl group, a C3-C8 cycloalkyl group, or an epoxy group. Processes for mailing these derivatives and for using them in cancer treatment are also disclosed. |