| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb78b459e21bb4fd52850a12cab27387 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-14 |
| filingDate |
1998-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed5bcd8d31130c42a82aca3ee0c031f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c818b55e34ebcb8a14ec5c68d66723e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4fa475cde2c528a3df4f57c8d650ad6 |
| publicationDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5932738-A |
| titleOfInvention |
Process to chloroketones using oxazolines |
| abstract |
This invention relates to a process for the preparation of an alpha -chloroketone compound comprising the steps of (i) cyclizing an alkynyl amide to form a 5-methyleneoxazoline (ii) chlorinating the 5-methyleneoxazoline using trichloroisocyanuric acid to produce a chlorinated oxazoline intermediate and (iii) hydrolyzing the chlorinated oxazoline intermediate with an aqueous acid to produce the desired monochloroketone wherein Z is alkyl or substituted alkyl, aryl or substituted aryl, heteroaryl or substituted heteroaryl or phenylene, R is a hydrogen atom or alkyl and R1 and R2 are each independently an alkyl or substituted alkyl group, or R1 and R2 together with the carbon atom to which they are attached form a cyclic structure. Additionally, when R is a hydrogen atom, a dichloroketone can be conveniently formed through adjustment of reaction conditions. |
| priorityDate |
1997-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |