| abstract |
Disclosed are compounds of the formula or the pharmaceutically acceptable salts thereof wherein: G represents a group of the formula where Ra and Rb represent hydrogen, or organic or inorganic substituents; A is an optionally substituted alkylene; R1, R2, R3, R4 represent organic or inorganic substituents; R5 is hydrogen or lower alkyl; R6 and R7 independently represent hydrogen, lower alkyl; or together form a ring of 5-8 members; Z is nitrogen or carbon; and W is optionally substituted aryl or heteroaryl. Compounds of the present invention demonstrate high affinity and selectivity in binding to the D3 receptor subtype. |