Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
filingDate |
1995-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f535a0ba00e985b2556920744cc26281 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e582d5a9fffb7d1a6bfeaf1ef3b7ba3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ca45d7ed8ffe4bc34d582f25d218259 |
publicationDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5932699-A |
titleOfInvention |
Retinoid X receptor-interacting polypeptides |
abstract |
Disclosed is a method for determining whether a test protein is capable of interacting with a retinoid X receptor protein. The method involves: (a) providing a host cell which contains (i) a reporter gene operably linked to a protein binding site; (ii) a first fusion gene which expresses a first fusion protein, the first fusion protein including a retinoid X receptor protein covalently bonded to a binding moiety which is capable of specifically binding to the protein binding site; and (iii) a second fusion gene which expresses a second fusion protein, the second fusion protein including the test protein covalently bonded to a gene activating moiety; and (b) determining whether the test protein increases expression of the reporter gene as an indication of its ability to interact with the retinoid X receptor protein. Also disclosed is purified DNA encoding retinoid X receptor-interacting proteins and the polypeptides expressed from such DNA. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7365160-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7122653-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2002168783-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2376947-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7425418-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003170738-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006287503-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005107590-A1 |
priorityDate |
1995-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |