| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e96496a9949403e2af2ca913e65bfec |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-472
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1996-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f79ce0d8d63d6ff565526e40de72589a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6510ac6b3849bfcce53369f449f6c0d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26e3045f42e0e4a6651921f8722863f9 |
| publicationDate |
1999-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5932483-A |
| titleOfInvention |
Synthetic peptide and its uses |
| abstract |
The invention provides a fragment of C1q which is characterized in that a plurality of such fragments selectively binds immune complexes or aggregated immunoglobulins in the presence of monomeric immunoglobulin. The invention also provides a synthetic peptide comprising the sequence: - Leu Glu Gln Gly Glu Asn Val Phe Leu Gln Ala Thr - 1 5 10 - [SEQ ID NO 2] - or variants thereof capable of binding immunoglobulin. Like the C1q fragment, a plurality of the peptides can selectively bind immune complexes or aggregated immunoglobulins in the presence of monomeric immunoglobulin. As a result of this property, the fragments and peptides are well-adapted for removing immune complexes and aggregated immunoglobulins from fluids containing monomeric immunoglobulin, and for detecting or quantitating immune complexes in such fluids. The invention also provides a binding material for removing immune complexes or aggregated immunoglobulins from a fluid. The binding material comprises plural binding peptides, the peptides being characterized in that a plurality of them selectively binds immune complexes and aggregated immunoglobulins in the presence of monomeric immunoglobulin. The invention also provides methods of treating an inflammatory response and prolonging the survival of transplanted tissue. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10179803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011218157-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107531799-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009105138-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009137050-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815813-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10927188-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9447145-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20170042792-A |
| priorityDate |
1990-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |