| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
1997-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c8c63deb6613bbd179fcba10d02b244
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85dbceececbaa314162d3d89520d69bd |
| publicationDate |
1999-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5928941-A |
| titleOfInvention |
Repressor kruppel-like factor |
| abstract |
Disclosed is a novel mammalian protein designated repressor Kruppel-like factor (RKLF). RKLF is a zinc finger protein that binds to a CACCC element in DNA, thereby repressing gene transcription. An isolated DNA encoding RKLF, vectors and cells containing the DNA, and RKLF-specific antibodies are also disclosed. The RKLF DNA or protein can be introduced into the tissues of a mammal to inhibit neoplasia or hyperplasia. Also disclosed is an in vitro screening method for identifying a compound that induces RKLF gene expression. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0168856-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0183541-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004091878-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6365379-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003082561-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0020622-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0168856-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003134350-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2364051-A |
| priorityDate |
1996-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |