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filingDate 1997-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1999-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4604ae53fb411c861e0b5e6202e40ab0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d489a0714be8598e251940ccb437c64
publicationDate 1999-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5919127-A
titleOfInvention Oviductal catalase binding to the membranes of spermatozoa and uses thereof
abstract The present invention relates to a novel oviductal catalase having a molecular weight of about 60 KDa and which binds to a spermatozoa membrane outer surface, wherein said catalase once bound to the spermatozoa membrane outer surface protects said spermatozoa against oxidation. A method of stabilizing spermatozoa membrane and improving spermatozoa survival during migration in oviduct and/or uterus for artificial insemination; which comprises coating spermatozoa with such a catalase enzyme. A method of improving spermatozoa survival during migration in oviduct and/or uterus in cases of female infertility due to the absence of endogenous catalase in the genital tract of the female subject; which comprises administering catalase in the female genital tract before co+E,uml i+EE t or coating spermatozoa with a catalase enzyme for artificial insemination. Also provided herein are method of diagnostic of male or female infertility.
priorityDate 1997-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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