Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2613944636ab2fdf3f83ef2d4b304f0 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-70 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-446 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-076 |
filingDate |
1997-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1999-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4604ae53fb411c861e0b5e6202e40ab0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d489a0714be8598e251940ccb437c64 |
publicationDate |
1999-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-5919127-A |
titleOfInvention |
Oviductal catalase binding to the membranes of spermatozoa and uses thereof |
abstract |
The present invention relates to a novel oviductal catalase having a molecular weight of about 60 KDa and which binds to a spermatozoa membrane outer surface, wherein said catalase once bound to the spermatozoa membrane outer surface protects said spermatozoa against oxidation. A method of stabilizing spermatozoa membrane and improving spermatozoa survival during migration in oviduct and/or uterus for artificial insemination; which comprises coating spermatozoa with such a catalase enzyme. A method of improving spermatozoa survival during migration in oviduct and/or uterus in cases of female infertility due to the absence of endogenous catalase in the genital tract of the female subject; which comprises administering catalase in the female genital tract before co+E,uml i+EE t or coating spermatozoa with a catalase enzyme for artificial insemination. Also provided herein are method of diagnostic of male or female infertility. |
priorityDate |
1997-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |