| abstract |
N-Benzylazolium derivatives of the general formula (I), ##STR1## wherein Q is the remainder of an azole compound of the formula II ##STR2## possessing antifungal activity; Z is nitrogen or methine; n R 1 and R 2 are each independently a hydrogen atom or a group --OY in which Y is a group easily hydrolyzable under physiological condition!; n R 3 and R 4 are each independently a hydrogen or halogen atom, lower alkyl, lower alkoxy, lower alkylthio, (lower alkylcarbonyl)thiomethyl, carboxy or methoxycarbonyl; and n X - is a pharmaceutically acceptable anion, n as well as salts, hydrates or solvates of the compounds of the general formula (I) have antifungal properties. |