| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14effe3850d2129f863b969dac4f1db8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1133
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 |
| filingDate |
1995-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6bbdeef107b6b9d86885d06d86b452d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d911b294f25a77d1174fe88949e40ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b9f57a65cc47888063db8e1f212e469
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f4d9865fe2edcada9703a1696fd162e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_759a0fa221002d1ece7481c8f4befd19 |
| publicationDate |
1999-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5891840-A |
| titleOfInvention |
Stabilization of somatotropins by modification of cysteine residues utilizing site directed mutagenesis |
| abstract |
Novel modified or derivatized recombinant animal somatotropins. Methods for stabilizing recombinant animal somatotropins by modification or deletion of the Cysteine residues utilizing site directed mutagenesis to replace from one to four of the cysteine amino acid residues of said somatotropins with one or more different amino acid residues or by derivatization of (1) both cysteine amino acid residues in the small loop of said somatotropin, both cysteine amino acid residues in the large loop or the four cysteine amino acid residues in both loops of said somatotropin. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9211342-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011223151-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8865868-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8222209-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8513192-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8841249-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11045523-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010084173-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695226-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7998930-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102292349-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7884073-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102292349-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8779109-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008194477-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6878861-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7375086-B2 |
| priorityDate |
1988-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |