| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D249-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D249-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-12 |
| filingDate |
1997-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d0b9d4bca76f0d0317dfe8eaa0f5bde
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0676a1ef345baaefecf361bc96d90b33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c938709a9b0e420276720c3183bf95ea |
| publicationDate |
1999-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5880129-A |
| titleOfInvention |
Methods of inhibiting invasion and metastasis of malignant solid tumors |
| abstract |
A discovery underlying this invention is the concordance between particular cellular signaling mechanisms and cancer cell growth and metastasis. It has now been discovered that certain compounds inhibit the signal transduction required for the maintenance and driving of the malignant process. These compounds are also effective for the in vivo treatment of solid tumors and related disease states. This invention provides a method for the use of these compounds to inhibit the invasion and metastasis of malignant solid tumors in mammals. This invention further provides a method for using related compounds to treat diseases involving aberrant signal transduction pathways. Some of the compounds used in the methods of the present invention are novel and constitute another aspect of this invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7678391-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005142217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003215528-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8168232-B2 |
| priorityDate |
1989-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |