| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-683
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-6615 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-117 |
| filingDate |
1997-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1999-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_045536a0a34ed19bacdfcdc5d97e8c1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558e16b25894d2c464ad7e01c0d33988
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42ab139fcd083bdf7c43a9e43df401d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b378f82110c8c5eeccfacd45049c957
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d4086fc55ca85d1d41df9201d2d5e12 |
| publicationDate |
1999-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5880099-A |
| titleOfInvention |
Inositol polyphosphates and methods of using same |
| abstract |
The present invention provides compositions that are cell permeable antagonists of inositol polyphosphates. In addition, the invention provides methods for enhancing chloride ion secretion from a cell by contacting the cells with cell permeable antagonists of inositol polyphosphates. The invention also provides methods for enhancing chloride ion secretion in an individual by administering cell permeable antagonists of inositol polyphosphates to the individual. The invention additionally provides methods for alleviating a sign or symptom associated with cystic fibrosis in an individual by administering a cell permeable antagonist of inositol polyphosphates to the individual. The invention also provides compositions that are cell permeable agonists of inositol polyphosphates. In addition, the invention provides methods for decreasing chloride ion secretion from a cell by contacting the cell with cell permeable agonists of inositol polyphosphates. The invention also provides methods for decreasing chloride ion secretion in an individual by administering cell permeable agonists of inositol polyphosphates to the individual. The invention additionally provides methods for alleviating a sign or symptom associated with secretory diarrhea in an individual by administering cell permeable agonists of inositol polyphosphates to the individual. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010093648-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007111970-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9833420-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010144891-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7521481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859628-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009227686-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009170957-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9078908-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010256094-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010105631-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004204387-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919481-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010113613-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006035810-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011201694-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03024189-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8178514-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008306166-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006241086-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03024189-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009062403-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006106000-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7618954-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010173960-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009029951-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006258626-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011028719-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7648970-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010292157-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7745423-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011105626-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008312138-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007197452-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010168250-A1 |
| priorityDate |
1996-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |